Can we add an OnRead event script to a spell tome so that when the spell tome is read it updates a quest stage or completes a quest?

Or might it interfere with the spell being added to the player's spell book menu?

Or would OnContainerChanged be better and would this work when going from on the ground to the player's inventory, rather than from an NPC inventory or a chest to the player's inventory?

Cheers!

~.~

OnContainerChanged() works whenever the object is added to a container, whether from one container to another, world to container, or container to world.

You might be best using a quest alias, fill it with the tome, and add the script to the alias. You're looking for SetStage() functions or SetObjectiveCompleted() functions.