I'm the female, so does this mean when I ditch the husband I get an extra 50% gold magically deposited to my inventory? w00t!
Technically he would come out on top in that deal, since you're the one selling assorted dragon bits at the market for a heap of septims. He's just back in Whiterun (or wherever) talking about the Mudcrab he saw today.
More on topic though, probably the "Best" way to divorce is simply taking your spouse on a riveting adventure. Turn that Murder in the 1st Degree into a much more palatable Killed in Action. Plus, there's all the sympathy tail (literally in the case of Argonians and Khajiit) that comes with tragically losing your not-so-significant other to the harsh laws of the wilderness.