From what I've seen on these forums, it seems to be taken for granted that not only is "slavery" of androids evil, but that it's anologous to enslaving actual humans. Further, and even more baffling to me, there seems to be a consensus that the "android situation" should be a high priority, even the focus of the main questline. Presumably the apex of said questline would involve destroying the evil, evil Institute.
That entire premise is just asinine. Let's just grant, for the sake of argument, that "enslaving" androids is super, super evil. Are the rights of sentient toasters really something that should be a high priority for large, organized groups of people? Keep in mind this isn't a civilized region where agriculture, commerce, and security are all firmly established. The setting of Fallout is a wasteland where finding food and water is a really serious challenge. At least in Bethesda's Fallout, there isn't a single farm, ranch, or food-dispenser to be found as far as the eye can see. There are no safe, patrolled roads from location to location. There is no research and development* to be found. Can a large, organized group of well-intentioned people really find no cause more worthy of their time? There are actual human slaves belonging to various factions, and those factions are (presumably) less powerful than the highly advanced Institute. If you want to fight the good fight, wouldn't it be a better idea to target organizations that enslave actual humans first? If not because organic, genuine people are a higher priority, than at least because the ones enslaving them are easier targets?
*Except from the factions that inevitably end up being the enemies. The Lone Wanderer spent the majority of his time breaking or blowing up highly advanced, practical technologies.