is he based on this guy?
http://en.wikipedia.org/wiki/Harry_Callahan_(character)
Yep. It's an easter-egg in the game. That's from the movie Dirty Harry, where he claims that the gun he's holding (a .44 Magnum) is the most powerful revolver on Earth. (It was, at the time, now the most powerful revolver is Smith and Wesson Model 500 known as SW 500 for short)
Incidentally, the most powerful revolver in Fallout 3 is indeed, Callahans Magnum. A unique .44 Magnum. I guess the devs were Clint Eastwood fans.
Nice little easter-egg, IMO.