I never sneak unless I have to. I hate too much sneaking and espionage and talking.

I used sneaking then hitting them with the mezzmatron to get some of the harder targets for Strictly Business. Or ones I did not want to have to do as much fighitng my way out of.

I sometimes use sneaking when capturing slaves. The critical hit means their head has less chance of exploding or they run away.

I used sneak for the Wasteland Survivval Guide for the optional part of the mirelurk quest.

When it comes to fights I would rather run right at them with my large gun and turn them into a bloody mess, lol.

I never use sneak in fights.