Ok, so you did it, but by the time you finished, you were so rich it didn't matter. Also, the loot from the chest is relatively generic. So all this makes me wonder why it was added to the game - just something to grind out? I mean, if all you want to do is steal stuff, nobody is stopping you. You could do it regardless of the safe and the 125-job requirement.
I wonder if something better was suppose to be in the safe (a unique item like the Skeleton Key) and they just didn't get around to implementing it or they just couldn't come up with a balanced item. A couple of unique items that come to mind:
* A more powerful version of the Amulet of Articulation (almost max's out AC)
* Something that opens all locks
* Something that lets you climb vertically and enter/exit through windows
Regardless, as things stand, there's way, way, too many things to do that are more interesting than 125 side jobs. Kudos to you for doing it, though, 'cause omebody had to!