Like many of you I have been having the same issues with the game freezing as well, mostly at just one area how ever, that being the Citadel. The game first started to freeze and lock up in that area when I was returning with a Tesla Coil. Since it kept freezing every time I tried to enter, or walk around the outside perimeter of the Citadel I sent an email for possible solutions to the problem, and I got a reply about 48 hours later.
FREEZING/PERFORMANCE ISSUES:
1. Problems may arise if you have been playing the game for an extended period of time. Let the system cool down, then try running the game.
2. Please make sure that you have the most recent update for your PS3 console.
3. Remove the game data from the Playstation 3 Hard Drive. Files in the Game Data Utility folder, are saved settings for a game (i.e., controller preferences, brightness settings, etc.). These steps will NOT delete your save games. To remove a game data file from the PLAYSTATION 3:
a. In the XMB home menu, go to (Game) > [Game Data Utility].
Important: Make sure you select [Game Data Utility]. Do NOT select [Saved Data Utility], as this will delete all of your saved games files.
b. Highlight the game data utility file (i.e., name of a particular game you have been playing) you wish to delete.
c. Press the button and select [Delete].
d. Highlight "Yes" and press the button to confirm the deletion.
e. A message indicating the file is being deleted will appear.
f. A "Delete completed." message will appear once the file has been successfully deleted.
4. Try running it from another console. If the game works properly on another system, you may want to contact Sony to find out more about getting your PlayStation 3 serviced. If the game fails to run on multiple consoles, contact our Technical Support representatives for further assistance.
DISC READ ISSUES:
1. Remove the disc and reinsert it.
2. Insert the game with the label side up.
3. Check whether the disc is scratched or dirty. If dirty, wipe it gently with a soft cloth.
4. Make sure the disc has not been exposed to high temperatures, high humidity or direct sunlight. When discs will not be used for an extended period of time, store them in their cases. Stacking uncased discs or storing them at an angle can cause them to warp.
5. Try running it from another console. If the game works properly on another system, you may want to contact Sony to find out more about getting your PlayStation 3 serviced. If the game fails to run on multiple consoles, contact our Technical Support representatives for further assistance.
DISPLAY ISSUES:
1. Check that the input mode of the TV is appropriate for the connector in use on the PLAYSTATION 3 computer entertainment system.
2. There may be a problem with the cable in use. Try using another cable that is compatible with the PLAYSTATION 3.
3. If the video output settings on the PLAYSTATION 3 do not match those of the cable or TV in use, there may be no picture. If the screen goes blank, turn off the system. Then, with only the PLAYSTATION 3 and the TV connected, touch the system's power button for more than 5 seconds to turn the system back on. The video output settings will automatically be reset to the standard resolution.
4. The content may be of a format that is not supported by the system. Content of types not supported by the system will not be recognized. For information on supported formats, refer to the online user's guide.
CONTROLLER ISSUES
1. Make sure all peripherals (controllers, memory cards, etc) connected to the PlayStation 3 are certified Sony products. This can be determined by looking at the products and ensuring that they have the word Sony on them. Even controllers that may carry the PlayStation 3 logo may not be certified Sony products. Using non-Sony products are not guaranteed by Sony to work with all PlayStation 3 games.
I am sure most of you have done the above also, and in my case it worked. At least, it worked till after I complete d the "Who Dares Wins" quest, and I am no longer able to enter the Citadel without the game freezing once more. Thinking that it might just be lagging I left the game alone for a total of eight ( 8 ) hours and came back to find it still locked in the same position of just facing the door. I am currently waiting for a reply from Bethesda on this, since I have attempted this fix at least a dozen times.
While playing I also found several different errors and coding mistakes in places. Such as a ladder in the Sewer System that you can go up to and interact with. It comes up with the options "Open Ladder" and "Close Ladder" when you select it, looking up you can see through the man hole above it and see clear daylight above. I also found areas where the paper that is suppose to be on the ground is actually suspended up in the air, as if caught on something along the side of the wall. This led to some funny things as I was able to kneel down in the paper and find a tin can under it all.
Hopefully the tech guys and gals will pay more attention to this thread and offer up a better solution, since it gets difficult to play a game if you have left a lot of gear in one place and you are unable to retrieve it or complete mini-quests.