Here are the settings I have been playing Crysis 3 with and its runs fantastic. Averaging around mid 40's FPS. I recommend these settings over what Nvidia stated http://www.geforce.com/whats-new/articles/nvidia-geforce-313-95-beta-drivers-released so you don't lose the added DX11 features like tessellation. All in all, set it how you prefer and like. I wanted to share what I found worked nicely and looked great with the added benefit of the DX11 extras. Excuse any typos please.
1920x1080P
V-SYNC OFF
TXAA MEDIUM (2xT 1)
Game Effects VERY HIGH
Object VERY HIGH
Particles VERY HIGH
Post Processing VERY HIGH
Shading HIGH
Shadows HIGH
Water VERY HIGH
Anisotropic Filtering 16X
Texture Resolution VERY HIGH
Motion Blur Amount OFF
Lens Flares YES
My System
Alienware X51
i7 3770 (Stock Clock)
EVGA GTX 660 TI ( Memory OC to 6000MHZ, GPU Stock Clock Due to limited 330W PSU in X51)
250GB Samsung 840
8GB RipJaw-X
Blueray RW