Not sure if there's a thread on this yet, couldn't see one.
Bethesda released a 15 second video about the "Big Leagues" perk, with a montage of the player landing some gruesome kills with a baseball bat. https://www.youtube.com/watch?v=fvmifSyRxg8
But what's most interesting about this is the flash of the loot system at around the 10 second mark. It's a tiny little box that comes up automatically as soon as the NPC is killed. This seems to be confirmation that the game does not pause while looting, and that perhaps the loot menu comes up automatically (or can be set to automatic) if you're looking at a dead enemy?
Also really excited that it seems we'll be seeing more tiny snippets of gameplay ahead of release as they're likely to release videos about other perks too.