Hey everybody I was just wondering why (according to dialogue*) the Brotherhood shoots at ghouls. I thought they were the good guys, abandoning their primary objective to help the natives. I mean there is no way they get ghouls confused with super mutants, that's just impossible.

*The sentry for underworld, can't remember her name

For one, BoS and Ghouls never have been in the same picture. Notice the fact that no ghouls are in BoS? Secondly, Ghouls are radiated people, and really aren't supposed to come in direct contact with 'normal' humans... I'm sure if BoS had there way and the mutated FEV that eden gives you didn't kill everyone who had drank radiated water in their lives...The BoS would have told you to use it..