Find below 6 bugs which I've found that have been verified by multiple other sources and are known to not depend upon the system that is running the game.
1. Damage resistance is calculated incorrectly for energy weapons, as is critical damage. As of version 1.1.30, the paper damage for energy weapons is calculated without using the rifleman perk. So energy resistance ignores the rifleman perk, and critical damage also ignores the rifleman perk.
2. Having the live-target HUD mod for your power armor helmet turns NPCs hostile immediately. Same as berry mentats.
3. Level 4 vendors are bugged and won't stay at assigned settlements. This includes all the level 4 merchants except Vault-tec rep. They either stay at the location you found them, never show up at the settlement, or mysteriously disappear from settlements. Using various console commands can temporarily fix some of these issues.
4. Also Ron Staples' inventory is bugged - he checks to see if he is assigned to a general store instead of a restaurant, so you can't get his level 4 inventory.
5. The big settlement bug where when you leave via fast travel the statistics in your pip-boy become incorrect e.g. number of beds, water, food,defense fall to small numbers or even 0, and happiness at that settlement starts to go down rapidly. Can sometimes be avoided by walking out of the settlement some distance then fast traveling. This does not always solve the problem. People have suggested a variety of fixes, such as removing all TVs, putting rugs under beds, etc. I can say that at least coincidentally this problem started happening to me after I moved a TV from one house to another in Sanctuary.
6. Another settlement bug - if the original plants growing in a settlement are damaged during a fight, they can not be repaired. They will consume the proper resource, i.e. a tato to fix a tato plant, but the plant will remain broken. This only appears to happen to original crops; new crops planted after taking over do not seem to have this problem. I believe console commands can help to solve this by disabling and re-enabling the plant, but I'm not positive.
Please let me know if there is a better way to submit bugs. I know you want my rig info, but as an engineer I know you don't need that info for these bugs; I can include it in other bugs that seem system dependent. I also saw that thread that was trying to unify all bug reporting, but I'm not sure how often that thread is checked and if it even holds enough weight to bother adding my stuff to it. And I suppose I'll have no idea if this is ever brought to developers' attention and I guess I will have to live with that. Thanks for your time.