I have a bug in my game where I have to talk to Serena to advance the questline but when I try to press E to talk to her it does nothing. She follows me around and fights with me but I am unable to talk to her at all. She still does her dialogue when she sees new places and fights or we are just wandering around. I was wondering if anyone else has had this problem and knew of any fixes. Thank you.

In which Dawnguard quest exactly are you in ????

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"Unlike other followers, the option "I need you to do something." does not appear while conversing with her as a follower.

You will need to press and hold E in order to issue commands to pick up, sleep, attack, etc.