I was invisible in one of the Dark Brotherhood quests where you have to kill Valen Dreth. In on of the tables with a helmet I decided to grab the helmet and grab it around while invisible infront of one of the guards. He scratched his head, like if nothing was there.
And with an invisibilty/chameleon you can auto-escape your enemies, and then they'll act as if nothing happen.
Have they done something to counter-measure this?
Like they look for areas of noise, like if you jump and you land, you make noise, and therefore attract their attention. Some might flail their weapons around in hopes of hitting you. This is of course, if they see you turn invisible.
Some enemies should be immune to your invisibility, such as bears,wolves and animals with sense of smell.
Enemies with detect life stuff should also be able to see you invisible.
This way, Chameleon won't be godmode.