I agree with
a) Wide option of character models, more than just tattoos, hair colors and a bit of change in height. I think gamesas should aim for character models different enough in theory that we can eliminate that horrid disembodied coloured text that flys around attacking avatars. Sure we're at the mercy of everyone making basically the same character.
On the above posters point, I would definitely wanted to see more realistic females. Getting punched out by a normal lass, yeah that's cool. Getting thrown around by a stick insect with briast implants is just infuriatingly stupid. +1 to muscle size being related to relevent S.P.E.C.I.A.L. stats.
b) Cybernetics and ghoulification/supermutation should be in-game options after character creation. Cybernetics should also be very rare, to fit both the setting and the value augmentation would offer. When it comes to ghouls, gamesas should throw out the Bible regarding FEV there. Think up something else, too much FEV/too many supersoldiers would have been counterproductive to the Pre-War government. It just bugs me, they wanted a sheep populance and they wanted expendable weapons but I don't think they would have wanted to combine the two.
Unfortunately I'm having trouble imagining as much use for Intelligence as was in the eariler games, as I think most options should be down to the player's intelligence. But at least then the wasteland won't be as populated by extraordinarily high IQ geniuses as the rest of the internet. Why do games studios have to fight and die? War, war never changes : (