Never done that, personally. Actually, I pulled the FO3 song files out and burned them to a disc. I listen to it in my car.
No. No it wouldn't. (opinion, of course)
But, then, I've never been a fan of stuff like that. I don't "get" fantasy/medieval movies with modern soundtracks, nor do I understand the desire to stick Metal music (even the "epic fantasy" type) in Skyrim. Just not my thing, at all.
edit: ah, crap. Just noticed this is from three weeks ago. /sigh