But the game itself keeps on conspiring to send near -- or often directly to -- locations that have already been "Cleared". For example, I've spent most of 200+ hours working on establishing, building up, and defending settlements. Part of that involves establishing Supply routes. It is literally IMPOSSIBLE to create any route that does not pass near a map location (re)populated by baddies that think provisioners and their pack brahmas were meant for Target Practice. Then too, if a player uses fast travel to take shortcuts to current destinations -- which is what fast travel was designed for, to be used -- the method is to use a known location (Cleared) as a stepping stone to the new destination. But if a Cleared location has repopulated, that can often result in literally jumping into a firefight -- with foes that had theoretically been killed off.
As I have already said, why even bother to label any location as "Cleared"? It should instead be labeled "Known".