To be a little more detailed maybe the ghoul realizes he is turning feral and once he admires you he tells you a story a fanciful tale that has been spun by camp fires by Ghouls for decades about a cure for Ghoulisum. So he enlists your help to find it but you only have X amount of time to do so or your companion goes feral. This of course for cannon reasons would be a onetime only cure never to be replicated. I think that would be fun. What do you think?