Is there any functional limit where putting over a certain number of items in a container causes "issues."

It seems like when I pile a mountain of items into my chest, certain custom enchanted items go missing. There could be mitigating circumstances but it was enough to get me concerned. I also notice that with many items in a container access to adding and removing items slows way down.

In previous games I seem to remember that the weight value in the CK would allow a container to hold more items, but can't seem to find documentation if that is still the case. Storage capacity seems to be infinity regardless of the container properties.

I am just wondering if this might avoid such glitches, or if anyone else has experience this or has any insight on the matter.