This is a problem that has been plaguing me for a while now - I cannot load any of my saves. I originally put it down to corruption due to my use of the quicksave, but now whenever I exit the game I make a brand new hard save after reading about corruption from overwriting.
The problem is, none of my saves are loading, and I know that they aren't corrupted* because they used to load, and my mod load order hasn't changed. It will load, I will see the game world for a spilt second and it will go straight to the desktop. This is a recent problem.
I'm using the retail GOTY version as the Steam version was giving me the finger with regards to MGSO. My DVD drive has been giving me issues lately (making noises during boot like it's overspinning) but the disc check works and the game boots. I honestly have no idea what to do - I would like to think a reinstall would fix it but there's been no change to the game folder for a week or two and this problem has been there for a couple of days.
*they might be corrupted but it's very unlikely considering it's happened very suddenly.