That crash usually happens due memory to issues on removing all items, since the game has to quickly keep track of every item you have. It's particularly frequent if there are mod-added items as well. A way to get around is place all items you can on a nearby container and go empty handed, and if that doesn't work disable mods that add or change items.
Thank you very much. Your solution worked for me.
Thats one thing I hate about Fallout 3 and New Vegas: That there are to much items wich you don′t use! No wonder the game had to crash some time.