Or more seriously/realistically, do you just mean to have a large (still would need a lot of people/families) group/community that is put together with the sole purpose of being able to survive/get back on their feet independently through the use of technology after an incident? Wouldn't it be easier to have a proper (non-isolationist) town built around technology, than to have a huge isolated community (essentially a town) cut off from the rest of the country/world. The isolationist part could spell disaster and be the undoing of their little community if anything serious actually happened...
The main purpose is not really to get ahead in case of an apocalypse though (but that's a bonus), but to live a good life pre-apocalypse. I don't really think we'll get an apocalypse, but there might be a severe crisis down the road (which will make cities more dangerous with crime and civil unrest etc).
As for the degree of isolation I don't know what's realistic. Trade with the outside has to go on obviously (can't manufacture our own high-tech from scratch, to name one thing -- otoh the necessities for survival shouldn't depend on the outside). Ideally people would work within the community, and some might be well-off to begin with.
Size? I don't know, another thing to examine by looking at existing successful communities. This guy below moved with his family into the sparsely populated deep Nevada desert, from having been a successful urban businnesman, and he says he's happier than ever:
http://www.sfgate.com/cgi-bin/article.cgi?f=/g/a/2008/06/02/moneytales.DTL
I don't know how big the pre-existing community is, or even how close to each other they are, but still.