Hopefully this info will help.
I have an M17x AW laptop running GTX260M SLI, 4G and 2.8ghz Intel core 2 duo. Everything runs great with fantastic FPS at 1920X1200p - Very High graphics but the flickering is horrible. There's two scenrios that occur for me (one worse then the other).
The first which gives me really bad flickering throughout the whole game is when I enable my Hybrid graphics card (integrated) that Alienware offers.
When I have Hybrid off and am only running on my 260s everything is the same but the flickering only occurs in darker areas/levels when there's more lights/reflections etc. In this case there will be a short burst of low FPS, the flickering starts and when I leave those areas/levels it goes away. Still absolutely annoying and horrible to play with.
In both cases certain things won't appear in the game. For instance during certain cinematic clips (in game) when ships fly by or something crumbles, sometimes there will only be one ship instead of three or none at all but sometimes all three. Not sure if these are connected but thought i'd mention it.
I've tried other fixes and the only thing that really solves the issue is turning off SLI and running on one card but...that's makes me extremely unhappy.
I'm running with the Nvidia beta driver 267.24 with the updated C2 profile.