If you're referring to the decrease in max health as you become more hollow, there are a few ways to deal with it.
1) Find the ring that reduces the effect of the health loss, so at max hollowing you'll have 3/4 of your max health, and just live with it for the first playthrough. Learning the ropes of how to to handle bosses and mobs will have much more of an effect on your success than an extra 25% health.
2) Don't sin too much on your first playthrough. Sin increases how much your max health can be penalized as you continue to hollow.
3) Co-op to restore your humanity and undo it. Dark Souls 2 has something called Small White Sign Soapstone, which allows players to summon you for just a few minutes, after which your duty will be fulfilled and you'll be restored.
4) Curse and petrification are separate status effects in DS2. Curse causes you to hollow one level, reducing your max health as if you died once, but does not kill you. Petrification instakills you and hollows you several levels, having an effect similar to DS1's petrifaction, only less penalizing and much easier to cure.
Also, a general tip specific to Dark Souls 2: There's a "waterlogged" mechanic unique to Dark Souls 2, where when you walk through water or poison pools, you'll get soaked with the liquid. If you simply wade through it, you'll be only soaked up to your knees, and the effect will disappear quickly, but if you somersault through it to try and get through it faster, you'll be soaked head to toe, and it'll take longer for the effect to wear off. Being soaked with water means you'll have increased fire resistance but reduced lightning resistance, while being soaked with poison means continuous poison buildup until it comes off. So do not somersault through poison pools.
Also, Dark Souls 2 is probably my favorite game of the trilogy. Aside from not being as soul-crushingly bleak as the other titles, it introduced quite a few interesting mechanics and innovations, some of which were completely ignored when Dark Souls 3 was made.