I had the same happen to me, just with raiders. I was lucky though, had a Molotov ready. Not being able to flee out the door is something I consider an engine misdesign rather than a legitimate reason for dying, but up to you m8. It svcks though.
Now I really have to share my latest DiD start, and how awesome it is because of this selection of mods:
Loot reduction: http://www.nexusmods.com/fallout4/mods/1486/? (Loot from level-list reduced by 95-75%, no meat from most animals)
Item weight: http://www.nexusmods.com/fallout4/mods/1670/? (Because stuff has weight you know )
Hunger/thirst mod http://www.nexusmods.com/fallout4/mods/3443/? (Food and water doesn't heal. Gives an addiction that needs food & water each day)
Deadly rad storms http://www.nexusmods.com/fallout4/mods/829/?(set to 10% chance and 25dmg)
Crippled limb fix http://www.nexusmods.com/fallout4/mods/3017/?(no autorecovery, needs stim)
Craftable ammo: http://www.nexusmods.com/fallout4/mods/798/?
Carry weight adjustment: http://www.nexusmods.com/fallout4/mods/214/?(set to 100!)
So with loot reduction, what you find is HEAVILY reduced, and you can't get meat from almost anything before you've found a bunch of survival magazines. This coupled with the need for food and water, and reduced output from farms, makes for a very interesting gameplay. You now need to actually eat the Dandy Boy Apples and deal with the consequences. And you won't find much radaway either. Those doctors sure come in handy now! I actually had to buy food to plant in Sanctuary and I still haven't fed everyone. Also, food doesn't heal you anymore, it just keeps you out of hunger, so your only source of healing is the rare stimpack, and the occational doctor. And of course a good nights rest. (now all I need is an ambush@sleep mod!)
So Laura Black is now lvl 8, and is a very lucky gunslinger of stealthy awesomeness. Except it really doesn't feel that way. I have barely managed to keep myself alive through the first expeditions into Lexington, and I'm now even more afraid of ghouls as they rad me up and I have trouble enough as it is with keeping radiation in check. I'm running a bit low on ammo and safe-ish places to go, but I got a request from a farm to go look for some raiders holed up in an old satellite bunker. I'm looking for a locket, if you can believe it. But it seemed like a place I might score some ammo. I have enough food and water for at least 3 days, so off I go.
I make my way there and manage to get in seemingly ok. I'm out of stimpacks (got ambushed by some raiders in the forest on the way there, and had to use the last one). I sneak my way in, but MISS a raider to my left and his dog jumps me. The dog CRIPPLES my head immediately but I gun him down while my dog is ripping out the throat of the bandit. Ok, cool. I'm alive, but blind. Can't see a damn thing. I decide to use my last two mines, and set them up on either side. I sneak attack a raider and blasts his head of with my musket. One mine goes of, but no one else is coming. I go further down, see a raider, and blasts him. Suddenly I see a raider with a MINIGUN (and I've modded it's damage up from 8->12) which just UNLOADS on my ass as I get the [censored] out of dodge. I run away with a slimmer of health left as I hear the enjoyable shattering of caps behind me and one dead raider. Thinking the coast is clear I head back, and to my surprise find ANOTHER raider coming at me. I pop into VATS, 3% chance to hit (I'm BLIND) but I've got a crit loaded up. Push play baby, you're dead.
So I'm alive. Crippled and maimed, but alive. Now I hope to God one of them have a stimpack so I can survive the way home.
Good God Fallout is so much better when I make it a struggle.