Yes, OBSE works with the Steam version, I can confirm that as I've been doing it for quite a while.
Not every obse based mod will work though, I think ... I remember having issues with the Better Sound mod, for instance.
But it seems to work well with DR... although for some reason, I can't get the Momentum bar to work. Eventhough it's displayed, it just won't fill, not even a little bit.
Anyway, I'm having an issue with DR6, so I'd like to ask for clues :
Basically, I'm getting yellow exclamation marks whenever I kill an enemy with a ranged magic attack. Lightning based spell, to be more precise (Lightning Bolt).
As for the type of enemy, it's the same kind of dudes that killed the emperor at the beginning of the game, I can't remember how they are called.
I'm at the part with Baurus in the sewers for the secret meeting...
I'm not an expert in this, but I know yellow marks mean some meshes are missing, but I checked the folders multiple times, and I'm pretty sure all the DR meshes are there. As well as the textures...
It's the first time I encountered this issue with DR6, it worked pretty well on my previous installation... but for some reason, ever since I reinstalled the game along with many other mods (that work flawlessly too), I'm having this issue.
I tried installing both manually and using OBMM, it doesn't change anything.
The yellow exclamation mark appears right around the area where the spell hit the enemy, and remains there (not on the enemy's dead body, which shows the calcination effect with no problem, along with the steam).
http://img28.imageshack.us/img28/2407/yellowmark.jpg
Edit :
When I click on it using the console, it says "Bound Helmet" ff0ac3c7 :
http://img806.imageshack.us/i/yyellowbound.jpg/
Any clue ?