Not exactly. It will never come out in it's original form. https://www.youtube.com/watch?v=BPkHZfjK5z4
http://kotaku.com/we-hear-the-people-behind-dishonored-are-now-working-on-510646344
In 2016, a game called "Prey 2" will ship, but it will be from a different studio (Arkane), running on an different engine (Crytek), and will basically be a System Shock 2 spiritual successor rather than an open-world shooter. So there will be a "Prey" game but it will share nothing in common with what you've seen up to this point.