I don't even have HC Mode on most of the time. The only time I had HC on was when I did a playthrough to get the achievment.
Oh, and I've never done a DLC with HC mode on. What's the point in going through the trouble? To "have a challenge"?
I just find it way more enjoyable. But my meters almost never run into any difficulty. You can get by so easily on one meal a day and drinking water maybe three times a day. There is a ridiculous amount of the stuff around. I generally have something to eat and drink in the morning when I get up and then top up as needed through the day.
What I love about hardcoe mode is you need a Doctors Bag to heal your limbs and stimpaks heal over time. You can kill anything without hardcoe mode on just by spamming stimpaks; seriously. Doesn't matter how much damage you take if you spam stimpaks. When I see a pack of Dethclaws running at me when I'm on hardcoe mode... oh man. That is a challenge . Course being a sneak bases player, that also means I've done something wrong
It also would annoy the living hell out of me if I could walk around with all this infinite ammo. It is so stupidly unrealistic... I don't think I could ever adapt to not having to factor that in.
I honestly can't see myself getting Fallout 4 without hardcoe mode.
Anyway, digression over, I had very little difficulty in Dead Money? You can get adrenaline at the Auto-Doc so you don't need to sleep and there are enough Sierra Madre chips that you can get a limitless supply of food and drink from the vending machines. The fact the air slowly kills you was a fun challenge though! I liked that. It's meant to be a place so dangerous almost no-one has ever left alive. You can hardly complain about that!