Another very good point! I agree that Nora would be more likely to stay at Sanctuary Hills, and this would also give her a settlement to rebuild. And when she's off exploring, there would be other people there to keep an eye on things. Jack on the other hand would use the garage mainly for storage and weapon crafting. I'm sure there would be other temporary locations he could use to rest, heal, or keep a few items stashed until he returns 
Okay. First of all, I think it's safe to say that I have spent more time researching this game than anyone who does not have the word "Bethesda" on their paycheck. Secondly, many of the ideas and suggestions I have proposed are now starting to be confirmed, and so I do have something of a track record (including prediction many gameplay elements just from the original trailer back in June). Secondly, the reason I have suggested that we will spend time searching for our spouse and child is due in large part to comments made by none other than Brian T Delaney. In case you didn't know, he is the voice actor for the male protagonist. Here's what Mr Delaney said during his first two interviews about Fallout 4:
https://www.youtube.com/watch?v=1KC5rttlnC8&feature=youtu.be&t=9m44s
"He's a family man, he has a wife, or she has a husband, and you have a child, and you know, obviously there are things that you draw from, there's images that I had in my head during the whole 13,000 line adventure, as Todd Howard quoted, that like, all of the lines, no matter how nihilistic the line may sound, it's always rooted, it's always grounded in that reality. I'm a real person with a real family..."
https://youtu.be/nGnCrgw9BU0?t=14m51s
"What I found interesting was, because there's a voiced protagonist, some of the things you say, these are lines that, I think I can bring this up, there nuacned lines. Every line is nuanced, even the ones, honestly, even the nihilistic, brutal kind of line, it's always grounded in the overarching super-objective, which I can't reveal, but you'll understand when you play the game."
Notice the difference between the two highlighted portions. This clearly shows that we will be searching from our family during gameplay, especially as this information has been kept out of the second interview, which suggests Mr Delaney was politely asked not to mention this any more following the first one.