Annoying, yes. stop me from trying to play? nope.
Another thing I find, annoying, and lacking, is the lack of people saying things like "Watch it" when running over clutter, or when crouched and pointing at somone so i get the "steal" activation option, or locked door, no one mentioned anything about it like they did in Fallout 3.
But meh, not game breaking. Theres plenty of other things taking care of that department.
Oh God, I hated that in fallout 3.
YES THAT IS LOCKED AND YES I CAN SEE YOU EYING IT.
Like holy [censored], even at 10 charisma and very good karma, they'd bust your balls for looking in the general direction of a locked cabinet.