"yippee! This might take me places in game! Maybe they will lead me to the legion!" I couldn't be more wrong. Around the 3rd mission, you have to find out information from Primm seeing if the NCR is going to take over the powder gangers base. Oh [censored] siege warfare by the looks of it, this should be fun. No, if your this far betray the Powder Ganger [censored]ers. The NCR blows some dynamite on the walls, and come storming in. Shooting you, and everyone around you with automatic weapons. One thing you will notice is that the powder gangers are falling like skittles from a rainbow, but the fact that your 1-5 level ass is no match for NCR. Time to run!
Guess what now numb nuts! YOUR A [censored] BANDIT NOW! Towns hate you, the NCR hates you, so travel will be all [censored] up. Not to mention that legion openly shoots holes into anyone, especially Powder Gangers. Go to Nipton if you don't believe me, they got a special cross for you. You are the reject of the wasteland, hope your survival, medicine, repair, and survival is up to par, enjoy your horrible life.
Now don't take this as the game has a hole in it, even though this quest line was disappointing, it made sense. The Powder Gangers didn't stand a chance, and when I start my character over, I'm going to try to make my way straight to the legion if I can, even if I have to do some NCR dirty work.