I've just tried to start my new playthrough, but as soon as the game started I found myself on a carriage which seemed to be totally out of control! I mean, the carriage was literally spinning all over the place and couldn't keep to the road. At times it seemed to even be trying to climb rock faces! Any idea why this could be happening? I've tried on both my old Mod Organizer account and my new one and it's the same thing, the carriage is all over the place.

FPS exceeds 60 -> physics go haywire. Don't let FPS go over 60!

You're not smuggling skooma over the border by any chance, are you?

How do I change that?

Are you trying to say that the Empire has trouble with soldiers smoking Skooma?

Assuming you have 60Hz monitor, the most simple solution would be enabing Vsync.

Alternatively, if you are using ENB, you can enable limiter in enblocal.ini.

Having a number of script intensive mods configuring simultaneously at the start of the game can also cause problems with the cart ride.

Not easy to smoke a potion....

Scratch all that. Someone on another forum said Realistic Ragdolls can do it. Logical really, when you think about, so I deactivated it and BINGO! So then, when can I activate it again safely?

I thought it was drunk too, but I had a check http://elderscrolls.wikia.com/wiki/Skooma_(Skyrim) and it says it's smoked. Then I checked http://www.uesp.net/wiki/Skyrim:Skooma and it says it is drunk!

Surprising with that massive list that you still do not use Wrye Bash for the Bashed Patch.

I used another program called "Merge Plugins xEdit Script" to merge a lot of my mods. I used an earlier version to merge most of my armour and weapons, as well as a few very basic mods like a banner one and one for retexturing potion bottles, that sort of thing. I believe more up to date versions allow you to merge major mods with scripts, but I decided to play it safe and just merge the basic stuff. As far as I can see through testing it did a really good job. However, in the earlier part of my playthrough I used some heavily scripted mods that weren't working right, ones I had to uninstall because they were causing CTDs; that and several changes of hard drive seems to have been the main culprits in corrupting my previous playthrough. Never fear though, 'cause not everything went totally as planned for my character; almost, but not quite. I also wanted to do my diary from the very beginning. I didn't have my character fully developed when I started first time, but now I do this gives me the perfect chance to play a hardcoe version of my character.