I like just the decrease in intelligence or agility or whatever. blurred vision and stumbling is just annoying IMO. it's pretty hard to capture the feeling of being drunk in a videogame. The best thing to do is to get drunk and THEN play the videogame if you want that feeling... if you are 21 or over.
Wow is it 21 to drink alcohol at all there? How Draconian.
You raise a brilliant point though. I don't want the screen to go all fuzzy. Especially since when you're drunk that only really happens when you get rat-arsed, to use a lovely British expression