Currently starting up an energy weapons character and I am trying to think of a way to tie him to the enclave. Just been reading up on their history and looking at the time lines. A lot of the stuff happened with the enclave roughly 40 years before New Vegas. More modern time wise stuff happened on the east coast. There is a mention of Enclave in Chicago though. Just curious to some peoples thoughts. Maybe what factions I would help, or crush, etc.

If you're looking for a role-playing type thing,you'd have to kill all the factions. That's what the Enclave would have done.
That's also what I like to do,Enclave commander mod helps.