True... I am just a bit glad that we have atleast a few people working on Fallout games, that worked on them in the past. Be it here on FOO... or on New Vegas. It does not garantee anything, but it's still nice.
I do think though that gamesas will have to take Fallout 3 as canon, because it's Bethesda that ownes the IP now, and they are the ones who decide what is canon or not now.
So, depending on when and where FOO will take place, gamesas probably will have to take FO3 into account.
A question though... do we know when and where FOO will take place?