I run the game on Ultra settings, what Fallout preferred to me automaticly. I have i7-4770K and Graphic card is AMD R9 280X XFX Black Edition.
I have installed the newest drivers and customized the Fallout 4 prefs as told to prevent crashing - doesn't help.

When my game crashes I hear weird beeps a while after my screen have gone black and the screen doesn't get a signal from my pc anymore. Pc is still on after the crash, I have to reboot it using the restart button it has. When crashed even my keyboard doesn't get power - it is connected to the pc usb port. So please help

Update: It seems that my game crashes in every part of the story where something happens - I got past applying the points to this vault tec guy, and the next crash came when ran to the hills and dropped to the vault