Skillpoints: 6 + INT (5 = 11)
This puts more emphasis on INT influence and means you generally have less skillpoints available.
Carry Weigth: 50 + 20 * STR (5 = 150)
Again influence of STR is enlarged, while limiting overall carry weight. Given overall amount of loot of Fallout 3 and New Vegas this seems like a reasonable compromise being a pack Brahmin and carrying only what you need.
Hitpoints: 50 + 20 * END (5 = 150)
There's no hitpoints on level up. You'll need some more perks that influence your hitpoints to compensate compensate, but overal it puts more emphasis on armor
Action Points: 50 + 5 * AGL (5 = 75)
It would depend on AP cost, strictly speaking the highest AP cost would have to be 55. Taking a point from Project Nevada, there would be sprinting which cost AP.
Melee/Unarmed Damage: STR - 2 (> 0)
No influences unarmed as well.This will help STRENGTH be more of a focus for unarmed characters, because in Fallout 3 and New Vegas STR isn't needed for an unarmed character.
Endurance should also influences fire resistance.