Yeah, I'd like to see a few of them, sure. Hairy ones as well. And your initial reaction to meeting one would be "HOLY MOTHER OF - *pulls out your gun*" and he'd be like "Noooes, calm down :C " to which you reply..... nothing. You freeze. Then you'd be like "jeez, gotta lay off the Psycho, gives me hallucinations".
I actually had an idea where you meet a "friendly" (non-hostile at least) talking deathclaw for your first time. If the game would take place around the Great Lakes and the Mutant Liberation Army would be in, you could be talking to one of the leaders and he'd say "come with me, I want you to meet someone" and lead you to their mess hall, open the double doors and in there is a huge, battle-scarred, hairy deathclaw and you'll react like I previously mention but the MLA leader will shout at you to put the gun down, that he's not an enemy. Then you get to talk to the deathclaw, and I imagine them speaking with a kind of hissing, growling voice, using a very simple vocabulary (actually not like Goris, he's a bit too intelligent and his breed is extinct. I'm talking about the hairy "intelligent as dogs" deathclaws.) He'd also be kind of grumpy and unpleasant to you, but play your cards right and he'll come to accept you and be a powerful ally.