well the ending to new vegas has many choices
SPOILERS



NCR being defeated

c?ser being killed and destroyed his camp

these are two major factions and with fallout 4 supposing to be based in mojave how are they going to work this out i mean these are major things even the end to dead money you can send a gas cloud over the mojave
how will they work around these endings?

There's been absolutely no information reguarding Fallout 4.

So, whatever you read about Fallout 4 being in the Mojave. It's just a wild stab in the dark and based on nothing factual at all.

NOPE.avi
Fallout game, Jason Bergman said (translated from Norwegian), "You'll get no tips from me. But the Mojave Wasteland was a fun place to explore, wasn't it?".[
http://fallout.wikia.com/wiki/Fallout_4#cite_note-0

there has been a lot of speculations but this is heavily implying that it will be around the mojave

It's a single, throwaway, translated statement. That is NOT heavily implying anything.

Also some things to consider.

1)Bethesda are likely to be making Fallout 4. They control the licence, New Vegas was simply contracted to Obsidian to make New Vegas.

2)Bergman works for Obsidian. He wouldn't be involved in anything Bethesda was doing. He may also have been joking precisely to keep people guessing.

3)Bethesda likely wouldn't return to a location that was only just visited. I don't know of any series that would do that.

4)The Wiki is not a line directly into Bethesda. Anything like that is on there is purely speculation and -in this case- based on little actual evidence.

5)Bare in mind that a tranlation is not alwas perfect. Words may be mistranslated.

on any matter if the fallout series revisits the mojave or anything near the core region how will they handle this i mean seems hard to work in this kind of stuff
its not mass effect