I would agree, but think of vault 101, how you had to come back and help people, my thoughts are someone like a mad scientist might take over the vault and threatened you.
There might be a few object that may be important inside vault 111
You may be right, vault 101 seemed like a real home. Untill you left of course, but in all general i do believe you could re-enter at some point.
I would have to highly agree with you on that.
That would be upto the modders to build inside vaults, i don't think there going to let us do that.
Maybe a quest to go back and get one of those games for you pip-boy or maybe your pip-boy gets taking over and you got to prevent it from happening.