To give the ol DLC thing a break, why not talk about perks and stats? Luck and Charisma are my favorite stats, though Agility and Intelligence are a close second. I have always played a charismatic character since I played Fallout 2, and it is always loads of fun.
My favorite perks are easily Critical Banker, Nuclear Physicist, Wasteland Whisperer, and Blitz, even though it is broken. Some honorary mentions would be Pain Train and Mysterious Stranger.