I
much prefer using Wrye Flash (a port of Wrye Bash) for installation, as I'm so used to BAIN now, and prefer that infinitely to OBMM. Yes, I know FOMM is somewhat better than OBMM, but still, installing
and uninstalling via Wrye [B/Fl]ash is just flat out superior. IME, anyway.
As noted above, DarnUI is a must (like DarN, or DarkUId DarN, for Oblivion, of course).
If you want something a little more "hardcoe" than FWE (which, don't get me wrong, is very good) you might like ART (Arwen's Realism Tweaks; there's a RelZ thread on the first page here) - it's compatible with MMM and a number of other key mods. Worth a look, at least, IMO.
CASM is another must. As is something to get NPCs to S T F U about your character even
looking at items they own (or at locked doors/whatever), or simply knocking things over. Gah, that was annoying. :flamethrower:
I like DC Interiors, and similar mods, though some of them are a bit dodgy, so could do with some editing/cleaning/patching. Definitely worthwhile, even so. And at least one or two are basically fine, as is.
I also like Fellout, or Dynamic Weather. Either can be used with Enhanced Weather (rain, snow and the like), IIRC. But using them (FO and DW) together mightn't be so wise.
Groovatron's great for screenshots, if you're into that.
I don't mind the eXcalibr stuff either, or some of it, anyhow. Adds lots of guns, etc. A bit of fun, but - depending on your setup - could be tricky/inappopriate, alongside other mods.
There are body mods, a la Oblivion. And clothing/armour follows alnog similar lines, you could say. Likewise, weapons.
...
I don't know - what are you after, other than textures and possibly something FCOM-like?