So, it was daytime and whenever I would look towards the 2nd Strip gate that would take you to the Tops, Ultra Luxe, etc. and there were some drunken NCR troopers my game would freeze - no matter where on The Strip I was located. If I look at them right out of Lucky 38 or walked across the road to speak to the small-arms dealer then turned around and looked at all the drunken NCR right in front of the 2nd gate - the game would freeze. It got pretty annoying having to shut down my Xbox and reload my game multiple times, but eventually I did get around it by just leaving the Strip and coming back later..
I'm not sure what caused the freeze. Possibly all the NPC's located too closely to each other along with everything else on the screen. I have no idea.. but just a heads up about something that caused some constant freezing.