Hi,

The game freeze while loading quick save, it happens around 20% of the time (i.e. once every 5-6 times quick save is loaded).

The sound keeps playing but the load icon in the lower right corner of the screen freeze and the game stops responding.

Tried the following:

1) play the game in windowed mode, borderless.

2) install 1.3 beta update

3) add registry values in: HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\GraphicsDrivers

TdrLevel, DWORD value 0

TdrDelay, DWORD value 8

I'm using mods, but this is a new issue and the mods were not updated recently.

Its a corrupted save. Don't rely on quicksaves. You should manually save the game at least every 20 minutes, although more frequently is better.

That's unlikely, because the game loads fine after killing Fallout4 process and restarting the game.

BTW also tried updating graphics drivers.

So far nothing helped.

Still I hope you are making new manual saves along the way.

Have tried adding Fallout4.exe and the launcher exe to anti-virus exceptions?