My FNV freezes for some reason every 5-10 minutes, typically when I go through a loading screen but sometimes even when I'm just walking around.

Here's my mod list:

FalloutNV.esm
DeadMoney.esm
HonestHearts.esm
OldWorldBlues.esm
LonesomeRoad.esm
GunRunnersArsenal.esm
ClassicPack.esm
MercenaryPack.esm
TribalPack.esm
CaravanPack.esm
Interior Lighting Overhaul - Core.esm
AWorldOfPain(Preview).esm
NVR-Strip.esm
Project Nevada - Core.esm
Project Nevada - Equipment.esm
Run the Lucky 38.esm
ELECTRO-CITY - CompletedWorkorders.esm
ELECTRO-CITY - Highways and Byways.esm
Project Nevada - Rebalance.esp
SomeguySeries.esm
Interior Lighting Overhaul - L38PS.esm
EnclaveCommanderNV.esm
Mission Mojave - Ultimate Edition.esp
OWB Companion Teleport.esp
OWB Moddable FIDO.esp
OWB More Vendor Caps.esp
OWB Stealth Field Suit.esp
OWB Valence Extra.esp
OWB Valence Mask.esp
The Mod Configuration Menu.esp
A Better Boone.esp
NVR-NPCs.esp
NVR-Version_10.esp
Project Nevada - Dead Money.esp
Project Nevada - Honest Hearts.esp
Project Nevada - Old World Blues (No Cyberware).esp
Project Nevada - Lonesome Road.esp
Project Nevada - Gun Runners' Arsenal.esp
NewVegasBounties.esp
NewVegasBountiesII.esp
outsidebets.esp
EnergyWeaponDeNerf.esp
Armory_of_Xzax.esp
Armored Duster.esp
Colossus T49.esp
Project Nevada - T49XV Patch.esp
Realistic Power Armor.esp
AWOPDeadMoney.esp
Light Step ED-E.esp
NVBabyDeathclawCommander.esp
HonestHeartsCheats.esp
NVDLC04 Allegiance w Duster.esp
WeaponModsixpanded.esp
Project Nevada - WMX.esp
WMX-DeadMoney.esp
WMX-HonestHearts.esp
WMX-OldWorldBlues.esp
WMX-LonesomeRoad.esp
WMX-GunRunnersArsenal.esp
WMX-ArenovalisTextures.esp
WMX-PreOrderPackClassic.esp
WMX-PreOrderPackCaravan.esp
WMX-PreOrderPackMercenary.esp
WMX-PreOrderPackTribal.esp
EVE FNV - ALL DLC.esp
WMX-EVE-AllDLC.esp
Project Nevada - EVE All DLC.esp
Interior Lighting Overhaul - Ultimate Edition.esp
ILO - A World of Pain.esp
RagingBull.esp
HEV.esp
AWOPDeadMoneyVendorPatch.esp
AWOP Interior Music.esp
EVE FNV - NO GRA.esp
EVE FNV - NO DLC.esp
Omegared99 - Enb Transparency Fix.esp
JustAnArmorPack_NV.esp
JustAnArmorPack_WithCheatBox.esp
Russell.esp
TheInheritance.esp
Zan_AutoPurge_SmartAgro_NV.esp
Armor block 90.esp
Lighter Gold Bars.esp
weather mod old world blues.esp
Weather mod.esp
weather mod lonesome road.esp
weather mod dead money.esp
weather mod honest hearts.esp
Project Nevada - EVE No DLC.esp
Project Nevada - EVE No GRA.esp
Beards.esp
XVEnclaveBunker.esp
Project Nevada - XV Enclave Bunker Patch.esp
WMX-EVE-NoGRA.esp
WMX-EVE-NoDLC.esp
lexx-hh-letter-english.esp
The Lucky 38 Empire.esp
ZK13 - Return of the Eyebots.esp
HTRP-Daily Vendor Restock.esp
HTRP-Vendor Supply Refresh.esp
DoubleVendorMoney.esp
Men of the Wasteland.esp

Could be any one of those really. I'm not suprised with that many mods. You should be using a bashed patch or compatibility patches.

Have you run BOSS?

You can start disabling mods and archive invalidated if u use texture replacers. See if the issue goes away. Make a new manual save before you do this and don't overwrite it.

You should be doing that anyway with that many mods.

I always run BOSS after I install a new mod, but I never tried to use a bashed patch.

You might try it. It's a wrye flash thing so not sure what mod manager you use. No guarantee it will help.

Should be plenty of google info about it. Wrye FLash is the prog

Are you using the 4GB loader? The game crashes when it reaches 1.8 GB memory used without it, which happens quite quickly when using a lot of mods. That of course only helps if your system has 4GB or more RAM.