When I start up Fallout 4 I'm able to click to skip the intro and the "press any button to start" command but after that my mouse cursor isn't visible and no button inputs from mouse or keyboard seem to be recognized by the game.

The game worked fine last night the few times I loaded it up.

Running Windows 10, if it matters. Mouse and keyboard are wireless. Other information available upon request.

Thank you in advance for any advice.

Do you have a gamepad controller plugged in?