Hold on... Bethesda told a fantastic story here. All of you who complain that it wasmt exclusive enough alway had the option ( as with all Bethesda games) to ignore it and make your own. I'm not a programmer but I think you are asking far too much to expect them to make the ENTIRE game flow fluidly with your random gameplay choices. I played a reasonably good person and other than getting svcked into the dark brotherhood thing, I feel like its all been very well done. I dunno, be grateful
For what you have, IMO...
I'm sorry, but once again, no. This is easy stuff, so long as you simply have a design strategy to allow player choice.
Look at Alpha Protocol, (Obsidian Entertainment, again, incidentally,) and in that game, virtually no matter what choices were being given to you, you generally had three ways to respond to any situation - Professional, Aggression, and "Suave".
All that really took was sitting down and making the design choice to make every single conversation allow for three possible types of responses... and many of these did little more than change the next line or two of dialogue, although consistently picking options of a specific type would eventually lead to the game reacting to you as a consistent whatever personality type and giving you perks based upon your personality choices.
That's still ultimately a bit restraining - you may not necessarily want to be any of those three, but some fourth option, of course - but it still at least gives you SOME control over your choices.
While yes, my character avoids doing Dark Brotherhood when I don't want to play as a sadistic fiend just for the evulz, I would feel far too left out of the game to not play ANY of the quests I don't feel fit my character's personal choices - I'd basically only get to do two or three quests in the whole game! Bethesda could massively improve itself with the slightest amount of effort, but they just don't care. Not anymore, anyway.