So, if i leave him in charge everything will work out nicely? If i take charge ill end up having to exterminate tribes, or no?
Which more beneficial, house in change or yourself/ myself?
The short version is the tribes will support you only if you go to them and win their support. With the Securitrons the Omertas, White Glove Society, and Tops will naturally fall in line but it's best to meet with them and follow their quest-lines. The Tops aren't necessary to do anything because Benny is the problem you need to deal with.
The Great Khans, Brotherhood of Steel are trickier.
Boomers, less so.