I managed to get one game running normal on skyline after about 5 tries, and my FPS dipped to the 20s in some parts of the map when I was just walking around, no shooting, no explosives, just EPIC.
So now it's either motion blur hurr durr, flickerano & artifacto duo, or slideshow performance. I was honestly looking forward to some improvements in graphics performance and being able to tweak them, but now I'm left with an unplayable mess.
I've tried to set the advanced graphics all to 'Very High' and 'Extreme' but all ended up with same result. And here's the catcher, in the one game that the graphics were normal, everything was set to 'High' in the advanced graphics, I didn't touch anything in between transition to next map, yet the next map spawned with unbelievable flickering.
On the other hand...for some random reason, singleplayer seems to be working just fine...
I'm running twin HD5850s in CrossFire with Catalyst 11.5
EDIT: nevermind about playing fine in singleplayer...it's F'd up too, completely.