Gotta say the npc really does look better than Oblivion or Fallout, but the skin doesn't look as good as it http://aquageneral.files.wordpress.com/2009/10/vlcsnap-2009-10-16-15h41m10s23.jpg. And this has far more to do with just how the developers handled doing skin than any silly notion about consoles, "open world", or things like that. (not for developers: subsurface scattering really does http://www.youtube.com/watch?v=Q4GpfnUirXE&feature=related better and can be done very quickly)
The creek shot looks good except for the water, hopefully the pc version will at least be up to what was already done in http://img13.imageshack.us/f/fo32.jpg/
What I'm most worried about is lighting, it's been rather ugly since Oblivion, New Vegas is no better. Shadows might help somewhat but I'd just like to see a lot more lightsources and etc. Similar tech as GTA4 and etc. used has been out for years and is actually faster than the old way of doing things. It's so well researched that I'm sure two months or so would have it up and running.