Generally speaking, Skyrim is pretty stable for me. Running 80 mods or so without CTDs and I've been careful about what I install. The only thing that I do get is infinite loading screens sometimes. There doesnt seem to be any rhyme or reason to it in regards to particular mods. I can start new games fine but when I load the save no dice. Doesnt always happen though.

What is typically the cause of infinite loading screens? Mod conflicts? Too many texture mods? Asking too much of my (rather beefy) computer?